Sometimes a medication that works wonders for one health issue can turn out to be useful for patients with a completely unrelated condition. One such drug is naltrexone. Initially approved by the FDA in 1984 as an anti-opioid, lower doses of naltrexone were soon discovered by Dr. Bernard Bihari to have benefits for those suffering from immune system dysfunctions. Gradually doctors began to use low-dose naltrexone (LDN) to treat their patients suffering from the effects of auto-immune diseases, cancer, and HIV. LDN helps to increase endorphins and decrease inflammation in patients, thereby enhancing a patient’s quality of life.
LDN is not a mass-produced medication. It has to be prescribed and administered in specific strengths and dosages that target the needs of each individual patient. The drug is made by accredited compounding pharmacies like Acton Pharmacy and Keyes Drug in collaboration with health care providers.
What Is Low-Dose Naltrexone (LDN)?
As an opioid antagonist, LDN blocks opioid receptors, beta-endorphin, and metenkephalin. In other words, it does not allow the body’s tissues to receive endorphins. Thus there is an increased release of endorphins and enkephalin. When taken at bedtime, in lower doses of 1.5 mg-5 mg, the drug can bring about a brief blockade of opioid receptors between 2 – 4am. This blockade is believed to up-regulate vital elements of the immune system. LDN has been shown to be beneficial for patients with HIV, lupus, auto-immuned disorders, pain and some cancers.
What Diseases Respond to LDN?
- Alzheimer’s disease
- Ulcerative Colitis
- Crohn’s Disease
- Sjogren’s Syndrome
- Weight loss
- Multiple Sclerosis
- ALS (Lou Gehrig’s disease)
- Ankylosing spondylitis
- Traumatic Brain Injury (TBI)
- Lyme Disease
- Chronic pain
- Parkinson’s disease
- Thyroid disease
and many more. Contact us or your physician to find out if LDN may be beneficial to you.
What Are the Side-Effects of Low-Dose Naltrexone?
LDN has few side effects. Some common ones are:
- Vivid dreams, usually only lasting a few days; if necessary, the time of dose could be adjusted to the morning
- Increased thyroid sensitivity; in this case, it may be necessary to adjust the medication
- Flu-like symptoms; if symptoms persist for more than 24 hours, the dose may be reduced until symptoms resolve
- Stomach cramps and diarrhea may occur but are rare
Low-Dose Naltrexone Dosage Forms
Taking LDN in oral capsules is the most cost-effective. Our compounding pharmacists can make capsules that are free from lactose and other allergens. For patients who have difficulty swallowing capsules, we can also make LDN in liquid form, or as needed in certain medical conditions, we can make LDN topical creams as well. Dinno Health will work collaboratively with your physician to provide you with the best dosage form.
Choose Dinno Health to Fill Your LDN Prescriptions
Dinno Health works alongside physicians and health care providers to create compounded medications, including low-dose naltrexone, that meet their patient’s specific needs. Compounding is offered at Acton Pharmacy (accredited by PersonalMed and PCAB) and Keyes Drug (accredited by PCAB.) Our pharmacists and technicians have completed advanced training to ensure the quality of compounded medications and are committed to meeting the highest standards of our profession. Choose Dinno Health to fulfill your LDN needs. Contact us today!
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A health care provider must prescribe a compounded medication. All compounding pharmacies – as is the case with all pharmacies – are required to operate under the governmental oversight of the state board of pharmacy, and in compliance with applicable regulatory bodies.